Nytricx Executive Summary
Nytricx develops nitric oxide (NO) releasing medical devices that mimic that natural release occurring in the human body. NO an endogenous gas produced primarily by the inner lining of blood vessels and numerous immune cells, has broad antimicrobial activity with no demonstrated microbial resistance. ​
The Company is currently focused on NO-releasing:
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Wound repair/healing patches (traditional and Fiber Optic)
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Fiber Optic catheter inserts (urinary and vascular)
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ePTFE coated endografts for aneurysm and peripheral artery disease
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Extracorporeal membrane oxygenation (ECMO) circuits
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Urinary and Vascular Catheters
Wound Repair/Healing
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The Nytricx wound patch incorporates a NO-releasing donor molecule into a wound repair patch that continuously releases NO for up to seven days.
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Nytricx Fiber Optic wound patch uses the intensity of light to control NO release, enabling precision control of both the level and duration of NO release.
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Both versions of the Nytricx wound repair/healing devices release NO gas which has is involved in the regulation and promotion of all four stages of the wound healing process, hemostasis, inflammation, proliferation, and remodeling.
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These devices are ideal for acute and chronic would treatments.​​​​
Fiber Optic NO-Releasing Wound Repair
Fiber Optic Catheter Inserts
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Nytricx novel fiber optic insert confers on standard Foley and peritoneal dialysis (PD) urinary catheters (UC) as well as intravascular (central venous catheters (CVCs), and peripherally inserted central catheters (PICCs), the ability to emit NO to prevent catheter infection, biofilm formation, and thromboembolism.
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The DCD insert confers, on the in situ catheter, the extensive biological properties of NO on both the extraluminal and intraluminal catheter surfaces, to combat infection, biofouling, and thromboembolism.
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Using a photo-initiated NO donor molecule, the DCD insert is incorporated into a polymer tubing, mounted on a side glow fiber optic, connected to an LED light source.
Fiber Optic NO-Releasing Catheter Insert
Light Intensity Controls NO Release
